Relative timing of mitochondrial endosymbiosis and the “pre-mitochondrial symbioses” hypothesis
نویسندگان
چکیده
منابع مشابه
The Alzheimer's disease mitochondrial cascade hypothesis.
We first proposed the mitochondrial cascade hypothesis of sporadic Alzheimer's disease (AD) in 2004. Our core assumptions were a person's genes determine baseline mitochondrial function and durability, this durability determines how mitochondria change with advancing age, and critical changes in mitochondrial function initiate other pathologies characteristic of AD. Since then several lines of ...
متن کاملMetabolic implications for the mechanism of mitochondrial endosymbiosis and human hereditary disorders.
The endosymbiosis of proto-mitochondrial prokaryotes (PMP) into proto-eukaryotic host-cells was a major advance in eukaryotic evolution. The nature of the initial relationship remains the subject of controversy. Various conceptual models have been proposed, but none has definitive support. We construct a model of inter-species interactions based upon well-established respiratory pathways, descr...
متن کاملP8: Temporal Lobe Epilepsy and Mitochondrial Dysfunction
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملThe Effect of Vitrification and in vitro Culture on the Adenosine Triphosphate Content and Mitochondrial Distribution of Mouse Pre-Implantation Embryos
Background: The mitochondria are an important source of adenosine triphosphate (ATP) production in pre-implantation embryo. Therefore, the objective of this study was to investigate the effect of vitrification and in vitro culture of mouse embryos on their mitochondrial distribution and ATP content. Methods: The embryos at 2-PN, 4-cell and blastocyst stages were collected from the oviduct of st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IUBMB Life
سال: 2018
ISSN: 1521-6543
DOI: 10.1002/iub.1950